THIS SITE IS FOR UK MIGRAINE PATIENTS WHO HAVE BEEN PRESCRIBED VYEPTI (eptinezumab)

VYEPTI®
(eptinezumab) for you

A medicine for helping to prevent migraines

VYEPTI is used to prevent migraine in adults who have migraine at least 4 days per month.1

For full information please refer to your Patient Information Leaflet (PIL).

For migraine patients who have been prescribed VYEPTI. Produced by Lundbeck Ltd. This website is not intended to replace the advice of your healthcare professional. If you have any questions about your medication, please speak to your doctor, nurse, or pharmacist.

This medicine is subject to additional monitoring. This will allow quick identification of new safety information. You can report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.
Please find full information on how to report a side effect on the bottom of this page.

What is migraine?

Migraine is a severe and painful long-term health condition. Different people can get different symptoms. When you have a migraine attack it can impact your daily life.2

Common symptoms may include:
  • A moderate or severe headache, usually on one side of the head3
  • Nausea, vomiting and sensitivity to light, sound, or strong smells2
  • Attacks with or without aura (flashes of light, blind spots, or tingling in the hands or face, which may come on before or during migraine)3
People with migraine are split into two types – ‘episodic migraine’ and ‘chronic migraine’ – depending on how many migraines they get a month.4

Living well with migraine

Making changes to your lifestyle and routine is one way to
help limit the impact of migraine on your life.5–7

Migraine management strategies could include:

Lifestyle

  • Good nutrition
    and diet5

  • Gradually reducing
    caffeine5

Sleep, exercise and environment

  • Maintain a regular sleep pattern6

  • Get some fresh air and exercise7

  • Avoid bright lights, loud noises or strong smells5

For more information about migraine triggers and management
strategies, take a look at the VYEPTI treatment starter pack.

Treatment starter pack

About VYEPTI

A medicine for helping to prevent migraines

You and your healthcare professional have decided that you may benefit from VYEPTI treatment. VYEPTI is given as a drip (infusion) into a vein.1

VYEPTI is a migraine-preventive treatment designed to help prevent migraines before they start.1
  • The recommended dose is 100 mg given every 12 weeks. Some patients may benefit from a dose of 300 mg given every 12 weeks. Your doctor will decide the right dose for you and how long you should continue to be treated.1
  • Your infusion will be administered by a healthcare professional and will take about 30 minutes, with additional time needed to set up the IV infusion.1
  • If you think you may miss your appointment or need to reschedule your infusion, contact your healthcare professional immediately to reschedule.
For more information about what you need to do on your infusion day, take a look at the VYEPTI infusion guide.
Vyepti infusion guide

Possible side effects

Like all medicines, VYEPTI can cause side effects, although not everybody gets them.

Contact your doctor or nurse immediately if you have any of the following side effects – you may need urgent medical treatment:1

Common (may affect 1 in 10 people): allergic reactions and other reactions due to the infusion. Reactions can develop quickly during infusion.
Symptoms of allergic reactions are:1
  • Breathing difficulties
  • Fast or weak pulse
  • Sudden drop in blood pressure making you feel dizzy or lightheaded
  • Swelling of the lips or tongue
  • Severe skin itching, rash

Serious allergic reactions are uncommon (may affect up to 1 in 100 people).

Other symptoms that may occur due to the infusion include respiratory symptoms (e.g. blocked or runny nose, throat irritation, cough, sneezing, shortness of breath) and feeling tired. These symptoms are usually non-serious and of short duration.1

Other side effects can occur with the following frequency:
Common (may affect up to 1 in 10 people):1
  • Stuffy nose
  • Sore throat
  • Fatigue

Before taking VYEPTI, tell your healthcare professional about any medical conditions, including disease affecting the heart and blood circulation. You also need to tell them if you’re pregnant (or planning to become pregnant), or breastfeeding (or planning to breastfeed). You should not be given VYEPTI if you are, or trying to become, pregnant.1

Talk to your healthcare professional before taking any medications for side effects or migraine.
For full information please refer to your Patient Information Leaflet (PIL).

Resources

Discover more about what to expect with VYEPTI treatment by watching this video that shares the first-hand experience of a real patient.

For more information about migraine and VYEPTI treatment, take a look at these resources (developed and funded by Lundbeck):

Reporting of side effects: If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in the package leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store.

By reporting side effects, you can help provide more information on the safety of this medicine.

This website is not intended to replace the advice of your healthcare professional. If you have any questions about your medication, please speak to your doctor, nurse, or pharmacist.
References:
  • Lundbeck VYEPTI Patient Information Leaflet (PIL).
  • ‘What is Migraine?’. The Migraine Trust. Available at: migrainetrust.org. Last accessed January 2024.
  • ‘Migraine – symptoms and causes’. Mayo Clinic. Available at: https://www.mayoclinic.org/diseases-conditions/migraine-headache/symptoms-causes/syc-20360201. Last accessed January 2024.
  • Lipton RB, Silberstein SD. Headache. 2015; 55(Suppl 2):103–22; quiz 123–26.
  • ‘Migraine attack triggers’ The Migraine Trust. Available at: migrainetrust.org. Last accessed January 2024.
  • ‘Migraine and sleep’ The Migraine Trust. Available at: migrainetrust.org. Last accessed January 2024.
  • ‘Migraines: simple steps to head off the pain’. Mayo Clinic. Available at: www.mayoclinic.org/diseases-conditions/migraine-headache/in-depth/migraines/art-20047242. Last accessed January 2024.
UK-VYEP-0293 | January 2024